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“We have … reported that acteoside inhibits the release of β-hexosaminidase from immunoglobulin E (IgE)-sensitized and … serum albumin-stimulated rat basophilic leukemia cells as well as the intracellular calcium level, release of histamine from, and production of tumor necrosis …-alpha and interleukin-4 in human basophilic (KU812) cells.”
“Moreover, acteoside inhibited histamine release, TNF- α, and IL-4 production in a dose-dependent manner from calcium ionophore A23187 plus phorbol 12-myristate 13-acetate (PMA) or compound 48/80-stimulated KU812 cells.”