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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Verapamil , but not diltiazem, increased the Kd of [3H]yohimbine binding from 2.03 to 46.99 nM without altering the calculated number of binding sites per platelet (124 sites/platelet).”
Effects of verapamil and diltiazem on human platelet function.“ Verapamil (10 microM) inhibited binding of [3H]-yohimbine (an alpha 2-adrenergic receptor antagonist) to intact human platelets (KD 10.5 nM vs 2.4 nM for control platelets) without altering the number of binding sites.”
“ Verapamil but not nisoldipine displaced [3H]-yohimbine from the specific binding sites on human platelets, suggesting an interaction with alpha 2-adrenoceptors.”
“ Verapamil but not nisoldipine displaced [3H]-yohimbine from the specific binding sites on human platelets, suggesting an interaction with alpha 2-adrenoceptors.”
“ Verapamil also inhibited the binding of a selective alpha 2-adrenergic antagonist, [3H]yohimbine , to intact platelets, and inhibited the binding of an alpha 2-partial agonist, [3H]clonidine, to platelet membranes.”
“phentolamine, prazosin, yohimbine , propranolol, methysergide, pentolinium or atropine but were inhibited by verapamil.”
6-[N,S-dimethyl-N'-cyanothioureidomethyl]-6,11-dihydro-5H- dibenz[b,e]azepine hydrochloride (Fran 12): a histamine and 5-hydroxytryptamine antagonist with pressor properties.“This latter component is blocked by Quin 2 and verapamil and also inhibited by yohimbine , an alpha 2 receptor antagonist.”
“3 Yohimbine (1–100 μm) reversed twitch potentiation caused by verapamil but not by Bay K 8644.”
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