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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Verapamil
supplement:
Levocarnitine
Research Papers that Mention the Interaction
“ l-Carnitine uptake was inhibited in BBM vesicles by valproate, verapamil , tetraethylammonium, and pyrilamine and by structural analogs of l-carnitine, including d-carnitine, acetyl-d,l-carnitine, and propionyl-, butyryl-, octanoyl-, isovaleryl-, and palmitoyl-l-carnitine.”
L-Carnitine transport in human placental brush-border membranes is mediated by the sodium-dependent organic cation transporter OCTN2.“The authors hypothesized that IV L-carnitine would increase both survival and hemodynamic parameters in severe verapamil toxicity.”
L-carnitine increases survival in a murine model of severe verapamil toxicity.“On the other hand, compounds such as verapamil and AZT were both able to inhibit both the skeletal muscle and the cardiac uptake of L-carnitine.”
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