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“Comparison of data from this trial with data from previous studies indicates that recurrent CDD may respond to a short course of high-dose vancomycin or to longer courses of low-dose vancomycin when either is combined with S. boulardii.”
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America • 2000 | View Paper
“There is level II evidence that S. boulardii combined with high‐dose vancomycin is more effective than the antibiotic alone in preventing recurrent Clostridium difficile diarrhoea.”
The Medical journal of Australia • 2008 | View Paper
“We report one case of fungemia caused by Saccharomyces cerevisiae occurring in an elderly patient treated orally with S. boulardii in association with vancomycin for Clostridium difficile colitis.”
“In animal models of C. difficile colitis initiated by clindamycin, animals treated with S. boulardii (at end of vancomycin therapy ) had a significant decrease in C. difficile colony-forming units, and of toxin B production.”
International journal of antimicrobial agents • 2000 | View Paper
“ S. boulardii in combination with vancomycin or metronidazole has not been shown to be more effective than either of these agents alone for treatment of a first episode of CDC.”