Possible Interaction: Vancomycin and Maltodextrin

“Overall, we conclude that (1) an increased maltodextrin concentration decreases vancomycin diffusion but increases the osmotic effect, leading to the optimum treatment condition, and (2) the combination of vancomycin and maltodextrin is more effective against S. aureus biofilms than either alone.”

“ Vancomycin and maltodextrin act together to increase the effectiveness of treatment against S. aureus biofilm growth.”

“We hypothesized that a combination of maltodextrin (osmotic agent) and vancomycin (antibiotic) would be more effective against Staphylococcus aureus biofilms than either alone.”