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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Valproic Acid
supplement:
Octanoic Acid
Research Papers that Mention the Interaction
“In the inhibitory experiments, some short-chain fatty acids, such as acetic acid, lactic acid, propanoic acid and butyric acid, and medium-chain fatty acids, such as hexanoic acid and octanoic acid , inhibited the uptake of [3H]valproic acid.”
Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo).“In summary, CA exerts acute anticonvulsant effects and potentiates the anticonvulsant effect of VPA at doses that result in plasma exposures comparable to those reported in epileptic patients on the MCT KD.”
Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice
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