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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Urokinase-Type Plasminogen Activator and Polyphenols

Research Papers that Mention the Interaction

One argument by Chung S. Yang was that the eVective concentration of tea polyphenols needed to inhibit urokinase (2–10 mM), suggested by Jankun et al. was at least three or four orders of magnitude higher than concentrations of EGCG normally expected in tissues (Yang 1997).
Archives of Toxicology  •  2008  |  View Paper
We investigated the ability of polyphenol fatty acid esters to inhibit the activity of serine proteases trypsin, thrombin, elastase and urokinase.
Journal of enzyme inhibition and medicinal chemistry  •  2012  |  View Paper