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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Kaempferol
Research Papers that Mention the Interaction
“Additional experiments showed that kaempferol treatment reduced the enzymatic activities and protein levels of matrix metalloproteinase (MMP)-2, MMP-9 and urokinase plasminogen activator (uPA) by gelatin and casein-plasminogen zymography assays and western blot analyses.”
“Collectively, our … that kaempferol attenuated the MAPK signaling pathways including ERK, JNK and p38 and resulted in the decreased DNA binding ability …-1, and hence, the downregulation in the expression and enzymatic activities of MMP-2, MMP-9 and uPA , contributing to the inhibition of … U-2 OS cells.”
Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells.
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