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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Linolenic Acid
Research Papers that Mention the Interaction
“This phenomenon may be explained by the fact that certain EFAs, such as gamma-linolenic acid (GLA) and eicosapentaenoic acid (EPA), inhibit uPA activity.”
The effect of essential fatty acids on growth and urokinase-type plasminogen activator production in human prostate DU-145 cells.“Oxidation of LA by lipoxidase especially increases tumour cell death, whilst GLA inhibits urokinase-type plasminogen activator (uPA) activity.”
“Both GLA (n-6) and EPA (n-3) acted as competitive inhibitors of UK with Ki values of 120 and 96 microM respectively.”
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