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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Diindolylmethane
Research Papers that Mention the Interaction
“ DIM also decreased the protein levels of uPA and MMP9, yet significantly increased E-cadherin protein expression.”
“Our results suggest that DIM can influence the cell migratory and invasive properties of human colorectal cancer cells and may decrease the invasive capacity of colorectal cancer through downregulation of uPA and MMP9 mediated by suppression of the transcription factor FOXM1.”
FOXM1-mediated downregulation of uPA and MMP9 by 3,3'-diindolylmethane inhibits migration and invasion of human colorectal cancer cells.
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