Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“We suggest that calcium is a second messenger of uPA , that this message is mediated in a CR3-dependent fashion, and that this signal primes neutrophils for superoxide production.”
“Our studies also demonstrated that increased intracellular calcium alters the synthesis of both uPA and PAI-2 in a manner which favors expression of PA inhibitor activity.”