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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Uridine Triacetate
supplement:
Grape Seed Extract
Research Papers that Mention the Interaction
“We found that GSPE treatment significantly reduced the number of motor neurons immunoreactive for hyperphosphorylated and conformationally-modified tau in the ventral horns of the spinal cord identified using AT100, PHF-1, AT8, and Alz50 tau antibodies.”
GSPE interferes with tau aggregation in vivo: implication for treating tauopathy“In addition, GSPE induced a reduction in immunogold labeling with antibodies against the C-terminal half (12E8, PHF-1) and the middle region of tau (AT8, Tau5, pSer214 tau, and AT180) but not the C-terminal end (Tau46).”
“We demonstrate that this GSPE is capable of inhibiting tau peptide aggregations, as well as dissociating preformed tau peptide aggregates.”
Grape seed polyphenolic extract as a potential novel therapeutic agent in tauopathies.
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