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Last Updated: 2 years ago

Possible Interaction: Urea and Polypeptides

drug:

Urea

supplement:

Polypeptides

Research Papers that Mention the Interaction

The production of biologically active eIF-4 alpha only occurs when the polypeptide is totally reduced during solubilization of the inclusion bodies in 8 M urea.
Protein expression and purification  •  1993  |  View Paper
The presence of urea during solubilization of collagenous samples for SDS PAGE had a marked effect upon mobility … certain rabbit antisera, antibodies from several human sera and binding of concanavalin A. When samples were solubilized with urea by … collagenous polypeptides was retarded relative to samples … to urea without heating.
Journal of immunological methods  •  1986  |  View Paper
The specific activity of individual polypeptides extracted by urea fell an average of 25% during the 10-day chase.
Current problems in dermatology  •  1980  |  View Paper
This difference in magnitude is caused by the temperature-dependent negative heat effect of additional binding of urea to the polypeptide chain of the protein upon its unfolding, which decreases the positive enthalpy of heat denaturation and increases the negative enthalpy of cold denaturation.
Biochemistry  •  1992  |  View Paper
The polypeptide resists denaturation by guanidinium chloride or urea but is totally inactivated by treatment with reducing agents.
The Biochemical journal  •  1984  |  View Paper
Once associated with the lipid bilayer, the vimentin polypeptide resists urea treatment, suggesting that it has become an integral constituent associated with part of the membrane.
Proceedings of the National Academy of Sciences of the United States of America  •  1982  |  View Paper
Sodium dodecylsulfate or urea dissociated cross-linked informofers into oligomeric polypeptides.
Nucleic acids research  •  1979  |  View Paper
Urea solubilized preferentially a polypeptide with a mol.
The International journal of neuroscience  •  1973  |  View Paper
This observation strongly suggests that urea interacts with sites common to the four different proteins, such as components of the polypeptide backbone.
Biochimica et biophysica acta  •  1971  |  View Paper
The hypocalcemic and leukocytosis-promoting activities of P-I were eliminated by treatments with heat, HCl, NaOH, urea and nitrous acid and weakened with nitrogen mustard.
Endocrinologia japonica  •  1968  |  View Paper
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