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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Urea
supplement:
Biochanin A
Research Papers that Mention the Interaction
“Key findings: The IP administration of BCA significantly decreased serum levels of urea , creatinine, uric acid and MDA and significantly increased serum CAT, GSH and TAC and cutaneous IL‐4 and GATA3 concentrations in the fifth and sixth groups compared to OVX‐DMSO and OVX‐ANA groups, respectively.”
Beneficial role of biochanin A on cutaneous and renal tissues of ovariectomized rats treated with anastrozole“Furthermore, the elevated serum creatinine and urea levels were lessened by some doses of biochanin A , indicating protection against renal injury.”
“The results … administration of Biochanin A (10 and15 mg/kg) after 42 days significantly reduced … of TGF-β1 and PAR-2 genes and FBG, urea , creatinine in serum compared to the Diabetic control group (P<0.001), … increased serum albumin compared to the Diabetic control group (P<0.001).”
Biochanin-A has anti-diabetic, anti-hyperlipidemic, anti-oxidant and protective effects on diabetic nephropathy via suppression of TGF-β1 and PAR-2 genes expression in kidney tissues of STZ-induced diabetic rats.
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