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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Ubiquinone and Ng-Nitroarginine Methyl Ester

supplement:

Ubiquinone

drug:

Ng-Nitroarginine Methyl Ester

Research Papers that Mention the Interaction

“Acute treatment with l-NAME (5 mg/kg), a nonspecific nitric oxide synthase inhibitor, significantly attenuated the antiseizure effects of subchronic doses of coenzyme Q10 in both seizure models induced by pentylenetetrazole.”
The effects of coenzyme Q10 on seizures in mice: The involvement of nitric oxide
Epilepsy & Behavior  •  2014  |  View Paper
“Combined treatment with Q10 and L-NAME partly abolished the effects of the inhibitor on the parameters of the LPO–antioxidant enzyme system and NO concentration.”
Effects of Endogenous Regulators of Endothelial NO Synthase on Nitric Oxide Homeostasis and Blood Serum Lipoproteins during Experimental Diabetes Mellitus
Bulletin of Experimental Biology and Medicine  •  2013  |  View Paper
“However, simultaneous application of L-NAME and simvastatin significantly decreased concentrations of both CoQ homologues in the left ventricle and slightly decreased CoQ(9) concentration in the skeletal muscle.”
Simvastatin decreased coenzyme Q in the left ventricle and skeletal muscle but not in the brain and liver in L-NAME-induced hypertension.
Physiological research  •  2007  |  View Paper