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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Tyrosine
drug:
Paclitaxel
Research Papers that Mention the Interaction
“It has been reported that taxol has additional effects in cells, including an increase in tyrosine phosphorylation of proteins and activation of MAP kinase.”
“These results demonstrate that taxol affects tyrosine phosphorylation of Shc and this may result in the activation of the Raf‐1/MAPK cascade.”
Taxol induces tyrosine phosphorylation of SHC and its association with GRB2 in murine raw 264.7 cells“We found that Taxol , like lipopolysaccharides (LPS), caused a marked increase in tyrosine phosphorylation of three proteins having M(r) of 40 (p40), 41 (p41), and 43 (p43) kd in RAW cells.”
“As a first step toward identifying signal responses shared by taxol and LPS, we have shown that taxol , as shown previously for LPS, rapidly induces the tyrosine phosphorylation of a 41- and 42-kDa protein.”
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