supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago
Research Papers that Mention the Interaction
“Among the 12 variants identified in fumarylacetoacetate hydrolase gene, 1 of them … prevalent in Spanish population is c.554–1 G>T. After NTBC … tyrosine and alpha-fetoprotein levels was observed in all the study groups, significant … no NBS-group (P = .03), especially in subacute/chronic forms (P = .018).”
Evolution of tyrosinemia type 1 disease in patients treated with nitisinone in Spain“ NTBC has resulted in a >95% suppression of HGA excretion with a concurrent rise in serum tyrosine (>500 μmol/L).”
“ NTBC and its metabolites influenced L-TYR catabolism differently.”
Influence of nitisinone and its metabolites on l-tyrosine metabolism in a model system.“A side effect of NTBC therapy is elevation of plasma tyrosine levels in a manner analogous to tyrosinemia type 2, another related condition which causes a painful palmoplantar hyperkeratosis and eye pathology described as conjunctivitis and herpetic-like corneal ulceration.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback