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Last Updated: 3 years ago

Possible Interaction: Tyrosine and Hypochlorite

supplement:

Tyrosine

Research Papers that Mention the Interaction

Cl-Tyr and diCl-Tyr were also formed from free tyrosine but then reacted further with HOCl.
In this study, we aimed to investigate the formation of Cl-Tyr from reaction of HOCl with tyrosine (both free and peptide-bound) and the fate of Cl-Tyr under such conditions.
The Journal of Biological Chemistry  •  2000  |  View Paper
At the same time, free tyrosine can influence MPO-induced protein oxidation due to its ability to modulate HOCl synthesis in the MPO active site.
Biochemistry (Moscow)  •  2019  |  View Paper
At pH 7.4 we detected an increased HOCl production in the presence of tyrosine not only by the MPO-H(2)O(2)-Cl(-) system but also in suspensions of zymosan-activated neutrophils.
Journal of inorganic biochemistry  •  2012  |  View Paper
The reaction of protein with HOCl resulted in changes in protein conformation as assessed by the UV fluorescence and oxidation of the unique methionine and tyrosine , chlorination of several lysines with formation of chloramines.
Free radical research  •  2002  |  View Paper
Amino acid analysis indicated that tyrosine was also degraded by hypochlorite , but we could not detect a carbonyl group formed at tyrosine.
Analytical biochemistry  •  1998  |  View Paper
Cysteine, tryptophan, and methionine were proven to be the most vulnerable amino acids for degradation upon hypochlorous and peracetic acid treatment, while tyrosine was only prone to degradation in the presence of hypochlorous acid.
Journal of agricultural and food chemistry  •  2011  |  View Paper