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Last Updated: 3 years ago

Possible Interaction: Tyrosine and Epigallocatechin Gallate

supplement:

Tyrosine

Research Papers that Mention the Interaction

EGCG also alleviates insulin resistance by enhancing tyrosine phosphorylated levels of IRS-1, stimulating the translocation of GLUT2, and activating PI3K/AKT as well as AMPK signaling pathways in a Bmal1-dependent manner both in HepG2 cells and primary hepatocytes.
Molecular nutrition & food research  •  2017  |  View Paper
Further analysis revealed that EGCG at low doses specifically inhibited HGF/SF-induced tyrosine phosphorylation of Met but not epidermal growth factor (EGF)-induced phosphorylation of EGF receptor (EGFR).
Experimental & Molecular Medicine  •  2011  |  View Paper
Our findings demonstrate that EGCG is a selective inhibitor of the tyrosine phosphorylation of PDGF-Rbeta and its downstream signaling pathway.
Quantification of the immunoprecipitated tyrosine-phosphorylated PDGF-Rbeta, phosphatidylinositol 3'-kinase, and phospholipase C-gamma1 by the enhanced Western blotting method revealed that EGCG treatment effectively inhibits tyrosine phosphorylation of these kinases in VSMCs.
Molecular biology of the cell  •  1999  |  View Paper
In addition, both tyrosine and serine phosphorylation of STAT1 are revealed to be suppressed by EGCG.
Journal of agricultural and food chemistry  •  2010  |  View Paper
EGCG acted at the level of preventing phosphorylation of tyrosines 1234/1235 in the kinase domain of the c‐Met receptor without effecting dimerization.
Molecular carcinogenesis  •  2010  |  View Paper
In contrast EGCG stimulated tyrosine phosphorylation of platelet proteins, including Syk and SLP‐76 but inhibited phosphorylation of focal adhesion kinase.
FEBS letters  •  2003  |  View Paper
EGCG caused a concentration dependent quenching of the intrinsic fluorescence of tyrosine residue in the FCP, indicating the occurrence of interactions between FCP and EGCG.
Guang pu xue yu guang pu fen xi = Guang pu  •  2015  |  View Paper
Luteolin and EGCG , but not quercetin, inhibited glucose load-induced insulin receptor substrate-1(IRS-1) tyrosine and Akt phosphorylation in adipose tissue.
Inflammation  •  2012  |  View Paper
This oxidation of deoxyguanosine, as well as the peroxynitrite-mediated nitration of tyrosine to 3-nitrotyrosine, was significantly inhibited by ascorbic acid, glutathione and (−)-epigallocatechin gallate , a polyphenolic antioxidant present in tea.
Experientia  •  2005  |  View Paper
EGCG inhibited tyrosine phosphorylation of PDGF beta-receptor and downstream activation of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways.
World journal of gastroenterology  •  2005  |  View Paper
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