Possible Interaction: Tyrosine and Calcium Supplement

“Based on these findings, the present study indicates that extracellular calcium suppresses tyrosine phosphorylation by decreasing the availability of intracellular ATP, and not by activating tyrosine phosphatases or inhibiting tyrosine kinases as has been previously suggested.”

“We clearly demonstrate that the presence of calcium in the external medium decreases tyrosine phosphorylation in both human and mouse spermatozoa.”

“In keratinocytes, calcium induced the tyrosine phosphorylation of a 65 kDa p120GAP-associated protein (p65Ca).”

“Therefore it was anticipated that calcium could directly affect the cellular L-phenylalanine turnover to L-tyrosine.”

“Thus the levels of [Ca2+]i and stored calcium appear to control tyrosine phosphorylation antagonistically.”

“Calcium-induced calmodulin conformational change and the influence of Ca2+ concentration on the electrochemical behaviour of CaM were evaluated, and significant differences, in the tyrosine amino acid residue peak potential and current, in the absence and in the presence of calcium ions , were observed.”

“The inhibitory effect of calcium on tyrosine phosphorylation was also observed in caudal spermatozoa using thapsigargin, a Ca(2+)-ATPase inhibitor that increased [Ca2+]i and precipitated a corresponding decrease in phosphotyrosine expression.”

“These results emphasize the pivotal role played by calcium and HCO3− in modulating the changes in tyrosine phosphorylation observed during epididymal maturation.”

“High doses of Y , Eu, and Dy markedly increased the accumulation of REEs in spleen and lungs as well as the concentration of Ca in liver, spleen, and lungs. (”

“ Tyrosine release by incubated SOL muscles from control and septic rats was increased when calcium was added to the incubation medium, and at a calcium concentration of 2.5 mmol/L, the increase in tyrosine release was greater in septic than in control muscle.”

“It has been suggested that calcium plays a role in the regulation of tyrosine hydroxylase [tyrosine 3-monooxygenase; L-tyrosine ,tetrahydropteridine oxygen oxidoreductase (3-hydroxylating); EC 1.14.16.21 activity.”