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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Tyrosine and Brivudine



Research Papers that Mention the Interaction

The interaction … the (E)-5-(2-bromovinyl)-2′-deoxyuridine deoxyribose ring with the protein is … by substitution of tyrosine 21 and phenylalanine 139 (analagous to herpes simplex virus type 1 histidine 58 and tyrosine 172), which may explain some of the differences in nucleoside sugar selectivity between both enzymes.
Journal of Biological Chemistry  •  2003  |  View Paper