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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Tyrosine and Atorvastatin

supplement:

Tyrosine

Research Papers that Mention the Interaction

First, we determined that atorvastatin inhibits the tyrosine phosphorylation of insulin receptor substrate (IRS)-1 through a decrease in the RhoA-Rho-kinase pathway, resulting in the inhibition of glucose uptake.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan  •  2018  |  View Paper
Atorvastatin inhibited IL-1β-induced Tyr phosphorylation of VE-cad by inhibiting RhoA and by dephosphorylating MLC.
In addition, atorvastatin inhibited monocyte-induced VE-cad Tyr phosphorylation in ECs and attenuated IL-1β-induced TEM of monocytes.
Experimental cell research  •  2012  |  View Paper