Possible Interaction: Tyramine and Tyrosine

“The inhibition of decarboxylation of tyrosine to tyramine and of tryptophan to tryptamine was studied at the initiation of therapy and again after chronic treatment with α-methyldopa.”

“ Tyrosine treatments enhanced the levels of DA, TA and their metabolites in the brain.”

“Abstract: The parenteral administration of L‐phenylalanine or p‐tyrosine increases the mouse striatal concentration of p‐tyramine , an effect that is enhanced by monoamine oxidase inhibition and reduced by an L‐aromatic aminoacid decarboxylase inhibitor.”

“ Tyrosine had no significant effect on CA metabolites in brain, but metabolites of tyramine and octopamine were increased 2- to 3-fold.”

“MK 485 + m‐tyrosine substantially reduced the levels of m‐tyramine and m‐octopamine in the heart, but their accumulation in brain was largely unaltered.”

“The results demonstrate that tyramine inhibits norepinephrine synthesis from tyrosine at the two hydroxylation steps.”

“The above results demonstrate that adding tyrosine and tyramine in the media significantly promoted the growth of the Lycoris radiata suspension cells and alkaloids accumulation in the cells.”

“… tyrA* … L-tyrosine (a competitive inhibitor with respect to prephenate), partly because the affinity for prephenate was reduced and partly because the Ki value for L-… is shown to result in multiple extra-domain effects upon the cyclohexadienyl dehydrogenase domain of the bifunctional protein.(ABSTRACT TRUNCATED AT 250 WORDS)”

“Hearts from reserpinized animals showed increased chronotropy after tyramine only when tyrosine was present in the medium.”