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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Tryptophan and Selective Serotonin Reuptake Inhibitors

Research Papers that Mention the Interaction

At typical doses for each of these compounds, neurochemical studies suggest a continuum of serotonergic enhancement from tryptophan through the SSRIs , fenfluramine and MDMA having the largest effect.
Biological Psychiatry  •  2010  |  View Paper
Moreover, there is circumstantial evidence suggesting that plasma tryptophan (TRP) levels can predict response to SSRIs.
These findings suggest that dietary TRP variations may affect the efficacy of SSRI in major depression.
Psychopharmacology  •  2004  |  View Paper