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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Tryptophan and Leptin

supplement:

Tryptophan

drug:

Leptin

Research Papers that Mention the Interaction

“On the other hand, leptin has been shown to favor Th1-type activity, which ultimately decreases tryptophan levels.”
Current medicinal chemistry  •  2013  |  View Paper
“The correlation between leptin consecutively was significantly associated with zinc and TRP in obese patients.”
Pakistan journal of pharmaceutical sciences  •  2017  |  View Paper
“ Leptin … Trp breakdown before and after the intervention (P < 0.02).ConclusionsSince disturbed metabolism of Trp affects biosynthesis of serotonin and might be associated with increased … and carbohydrate craving, strategies to supplement Trp while dieting could be highly useful in treating uncontrolled weight gain or in preventing neuropsychiatric symptoms.”
European Journal of Nutrition  •  2014  |  View Paper
“ Leptin , a pro-inflammatory cytokine, activates Trp conversion into Kyn.”
International journal of tryptophan research : IJTR  •  2021  |  View Paper