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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Tryptophan
supplement:
Cuprous
Research Papers that Mention the Interaction
“The results obtained indicate that the interaction between Cu(I) and tryptophan via π-electrons plays a significant role in protecting the thiolate-Cu(I) center against the oxidation.”
Copper(I) stabilization by cysteine/tryptophan motif in the extracellular domain of Ctr4.“For example, the indole ring of Trp has been reported to interact weakly with Cu(I) in a Cu chaperone CusF. Another aromatic amino acid, tyrosine (Tyr), has a phenol ring, which is an important metal binding site in various metalloproteins.”
“Its close proximity coupled with spectroscopic data suggests an unusual cation-π interaction between Cu(I) and the aromatic ring of tryptophan.”
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