Possible Interaction: Tryptophan and Calcium Supplement

“This finding and the inhibitory actions of Ca2+ -channel blockers on TRP responses and of the proctolin receptor antagonist on both peptides, may suggest that the LemTRP receptors are not on the hindgut muscle fibers but on the terminals of the proctolinergic neurons.”

“The intrinsic tryptophan fluorescence intensity (FI) of apo-CR reversibly increased about 3-fold upon addition of calcium , indicating a change of conformation.”

“Thus the activity of trp , and another Drosophila protein designated trp-like or trpl, may be linked to depletion of the internal Ca2+ store via the so-called capacitative Ca2+ entry mechanism.”

“This was demonstrated by an upshift (30-39 degrees C) of the transition temperature of the rotational parameter of the native tryptophans of CaATPase in the presence of calcium.”

“The fluorescence emission maximum of the single tryptophan shifts from 325 to 348 nm upon the removal of calcium and decreases in intensity by 50%.”

“These results indicate that there is a large increase in the accessibility of the tryptophan residue in the protein to solvent upon removal of calcium.”

“This indicates that calcium causes significant perturbations of tryptophan and tyrosine residues in DNase.”

“It was hypothesised that tryptophan would increase piglet survival and increase sow circulating melatonin and calcium.”

“The metabolome of fruit exposed to calcium also displayed substantial modulations, particularly in the levels of galactose, glycerate, aspartate, tryptophan , phospharate rutin, and peonidin 3-O-glucoside.”

“The enzyme exhibited high specificity for ATP with a K(m) value of 10 nM. Titration with calcium resulted in the enhancement of intrinsic emission fluorescence of swCDPK and a shift in the lambda(max) emission from tryptophan residues.”