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“ Trypsinization of cells leads to a decrease both of specific binding and of binding affinity (affinity constant after 60 minutes of trypsinization 0.5 X 10(6) M-1 versus 1.5 X 10(6) M-1 in untreated control cells).”
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme • 1987 | View Paper
“It inhibits trypsin and thrombin with second-order rate constants (Kobs/[I]) of 2.6 x 10(5) M-1 s-1 and 1.0 x 10(5) M-1 s-1, respectively, showing a 130-fold and a 1250-fold rate enhancement over the corresponding diphenyl ester (4).”
Bioorganic & medicinal chemistry • 1998 | View Paper
“It is a peptide of M.W. 3020 of strong inhibitory activity (Ka = 8 x 10(11) M-1 ) against trypsin , showing high Gly content, six half-cystine residues, but devoid of histidine, threonine, tryptophan, and tyrosine residues.”