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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Trypsin and Recombinant Human Chorionic Gonadotropin

Research Papers that Mention the Interaction

hCG levels ranging from 10 x 10(3) to 333 x 10(3) IU/L produced a dose-dependent inhibition of the in vitro globinolytic activity of the purified proteases trypsin , chymotrypsin, and urokinase, but failed to inhibit plasmin, collagenase, elastase, and tissue-type plasminogen activator.
The Journal of clinical endocrinology and metabolism  •  1993  |  View Paper
Cells that were preincubated with TR responded to hCG stimulation with increased progesterone secretion (P less than 0.01) in a fashion similar to untreated cells.
However, continuous exposure (3h) of cells to TR significantly depressed (P less than 0.01) basal P secretion and inhibited the response to hCG.
Steroids  •  1980  |  View Paper