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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Trypsin and Phosphatidylinositol 4,5-Diphosphate

Research Papers that Mention the Interaction

We identified 515 proteins with PIP2-binding capacity of which 191 ‘exposed’ proteins represent a direct PIP2 interactors and 324 ‘hidden’ proteins, where PIP2 binding was increased upon trypsin treatment.
Cells  •  2021  |  View Paper
Furthermore, trypsin digestion reveals a potential conformational change of PHF8 upon PIP2 binding.
Biochimica et biophysica acta. Molecular and cell biology of lipids  •  2018  |  View Paper
Trypsin induced PIP2 breakdown, which was maximal at 20 micrograms/ml, but was reduced at higher concentrations.
Archives of biochemistry and biophysics  •  1990  |  View Paper