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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Trypsin
drug:
Collagenases
Research Papers that Mention the Interaction
“Treatment of fluids with trypsin released both collagenase and elastase.”
Neutral protease, collagenase and elastase activities in synovial fluids from arthritic patients“It has been suggested that trypsin may contribute to the proteolysis of collagenase and the destruction of islet cells, or possibly exert indirect effects on the pancreas by activating other endogenous serine proenzymes.”
“Our research revealed that collagenase proves advantageous to proteases such as trypsin or dispase, especially in case of cell isolation after long postmortem times.”
“Disruption of the cytoskeleton by trypsin , EGTA, or cytochalasin C increased mRNA for collagenase by 3.8-fold, 2.3-fold, or 2.5-fold, respectively.”
“Small endothelial cell aggregates were released from first trimester decidua by the sequential use of collagenase and trypsin.”
“Interestingly, after exposing the patched cells isolated by trypsin to collagenase IA for 3 min, the α9nAChR sensitive SK2 current was abolished, while m2mAChR-sensitive BK current was activated.”
Two Distinct Channels Mediated by m2mAChR and α9nAChR Co-Exist in Type II Vestibular Hair Cells of Guinea Pig“ Trypsin and collagenase , when used together, were found to act synergistically.”
“Synoviocytes were separated by incubation of collagenase and trypsin , and morphological changes of synoviocytes were observed by transmission electron microscope.”
“The coefficient of reflection at cartilage surface decreased by 78.5% and 10.5% (p < 0.05) after 6 h of exposure to collagenase and 4 h of exposure to trypsin , respectively.”
“In 91% of atrial cells we observed both ICaT and ICaL when collagenase and trypsin were used to dissociate the cells.”
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