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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Triiodothyronine
supplement:
Resveratrol
Research Papers that Mention the Interaction
“Drugs that target the SIRT1 pathway, resveratrol and nicotinamide, modulate T3 response at dual TRβ1/SIRT1 target genes.”
SIRT1 is a Direct Coactivator of Thyroid Hormone Receptor β1 with Gene-Specific Actions“Addition of resveratrol increased the T3 induction of the pdk4 and cpt1a genes in hepatocytes.”
“… resveratrol at 350 or 500 mg/kg lowered (p < 0.05) the contents of corticosterone, adrenocorticotropic … of aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase, increased (p < 0.05) the levels of triiodothyronine , the ratio of triiodothyronine to thyroxine, total protein, glutathione, …, catalase, and glutathione peroxidase, though with few fluctuation.”
Effect of resveratrol on growth performance, rectal temperature and serum parameters of yellow-feather broilers under heat stress.“ Resveratrol significantly suppressed the release of osteocalcin stimulated by T3 , and SRT1720, a SIRT1 activator, significantly reduced T3‑induced osteocalcin release.”
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