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“In this issue of Thyroid, Chan et al. report that the pBi-L vector (Clontech, Mountain View, CA ) is negatively regulated by triiodothyronine (T3) (1).”
The Journal of clinical endocrinology and metabolism • 1959 | View Paper
“Conversely, both JH III and 3,5,3' triiodothyronine T3 ) increase the activity of Ca ATPase in isolated erythrocyte membrane preparations from sheep, apparently through the same membrane receptor.”
“ Calcium balance (g/day) was higher by 0.65, 1.39 and 1.40, respectively, in lambs fed rations T2 (p > 0.05) and T3 and T4 (p < 0.05) in comparison to those fed ration T1.”
“These studies suggest that T3 may augment myocyte calcium cycling via changes in both cAMP- and calcium/calmodulin-dependent protein kinase activities.”
“Permeabilization induced by T3 is dependent on Ca2+ (1 microM) and T3 (0.5-25 microM) concentrations and is inhibited by cyclosporin A, a known inhibitor of mitochondrial permeability transition.”