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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Trifluoperazine and Vitamin D

supplement:

Vitamin D

Research Papers that Mention the Interaction

Acute clearance experiments were performed in PTH-infused parathyroidectomized rats receiving 25(OH)D3 after pretreatment with trifluoperazine (TFP) or promethazine (P).
TFP but not P abolished the effects of 25(OH)D3 both in vivo and in vitro.
Thus, (1) TFP abolishes both the antiphosphaturic and the AC/cAMP-related actions of 25(OH)D3 , (2) P does not have these effects, and (3) R 24571 abolishes the in vitro effect of 25(OH)D3.
Pflügers Archiv  •  2004  |  View Paper
The calmodulin antagonists; W7, compound 48/80, trifluoperazine (TFP) and calmidazolium (R24571) were all found to effect a dose response inhibition of the 25 hydroxylation of cholecalciferol by homogenates of ovine liver.
Cell calcium  •  1987  |  View Paper