“Acute clearance experiments were performed in PTH-infused parathyroidectomized rats receiving 25(OH)D3 after pretreatment with trifluoperazine (TFP) or promethazine (P).”
“ TFP but not P abolished the effects of 25(OH)D3 both in vivo and in vitro.”
“Thus, (1) TFP abolishes both the antiphosphaturic and the AC/cAMP-related actions of 25(OH)D3 , (2) P does not have these effects, and (3) R 24571 abolishes the in vitro effect of 25(OH)D3.”