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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Trichosanthin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Increase of cytosolic free calcium played a pivotal role in apoptotic cells induced by trichosanthin.”
Increase of cytosolic calcium induced by trichosanthin suppresses cAMP/PKC levels through the inhibition of adenylyl cyclase activity in HeLa cells“…,TCS treatment induced a … elevation in intracellular calcium concentration and a slow increase in reactive oxygen species production, while calcium chelators and antioxidants had no obvious effect on TCS-… apoptosis, suggesting that calcium changes and reactive oxygen species may not be involved in TCS-mediated apoptosis in K562 cells.”
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