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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Triamterene and Folate

supplement:

Folate

Research Papers that Mention the Interaction

The diuretic drug triamterene has previously been shown to be a competitive inhibitor of folate absorption in the rat intestine (J Lab Clin Med 1986;108:272-6).
The Journal of laboratory and clinical medicine  •  1991  |  View Paper
Kinetic analysis using the … method demonstrated that triamterene is a … of intestinal folate transport, with a Ki of 0.125 mmol/L. Because therapeutic doses can result in luminal concentration of … drug approximating or exceeding the Ki, the interaction between triamterene and folate absorption is potentially of clinical interest.
The Journal of laboratory and clinical medicine  •  1986  |  View Paper