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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Tretinoin and Zoledronic Acid

supplement:

Tretinoin

Research Papers that Mention the Interaction

We demonstrated that the combination of ATRA and zoledronic acid is a strong inducer of apoptotic related cell death in human androgen-and drug refractory prostate cancer cells DU-145, at either transcriptional or translational levels.
We report that all-trans retinoic acid (ATRA) in combination with zoledronic acid has strong synergistic cytotoxic and apoptotic effects against human hormone- and drug-refractory prostate cancer cells, PC-3 and DU-145, in a time- and dose-dependent manner.
Molecular Biology Reports  •  2010  |  View Paper