supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Tretinoin
drug:
Trifluoperazine
Research Papers that Mention the Interaction
“CaM antagonist, trifluoperazine , enhanced TRA‐8 activated DR5 oligomerization, DR5‐mediated DISC formation, and TRA‐8 activated caspase cleavage for apoptosis, and decreased anti‐apoptotic pERK, pAKT, XIAP, and cIAP‐1 expression in TRA‐8 resistant TNBC cells.”
Calmodulin antagonist enhances DR5‐mediated apoptotic signaling in TRA‐8 resistant triple negative breast cancer cells“ TFP decreased TRA‐8 activated DR5 oligomerization, which was consistent with TFP's effect on DR5‐mediated DISC formation.”
“ Retinoic acid , an antitumor‐promoting agent, was inhibitory and trifluoperazine , an inhibitor of calmodulin‐dependent processes, had a minor inhibitory effect.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback