Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Tretinoin and Trifluoperazine

supplement:

Tretinoin

Research Papers that Mention the Interaction

CaM antagonist, trifluoperazine , enhanced TRA‐8 activated DR5 oligomerization, DR5‐mediated DISC formation, and TRA‐8 activated caspase cleavage for apoptosis, and decreased anti‐apoptotic pERK, pAKT, XIAP, and cIAP‐1 expression in TRA‐8 resistant TNBC cells.
Journal of cellular biochemistry  •  2018  |  View Paper
TFP decreased TRA‐8 activated DR5 oligomerization, which was consistent with TFP's effect on DR5‐mediated DISC formation.
Journal of cellular biochemistry  •  2017  |  View Paper
Retinoic acid , an antitumor‐promoting agent, was inhibitory and trifluoperazine , an inhibitor of calmodulin‐dependent processes, had a minor inhibitory effect.
European journal of immunology  •  1984  |  View Paper