“Recent work shows that topical all‐trans retinoic acid (tretinoin) prevents skin atrophy in mice treated with topical corticosteroids , but such studies have not been performed in humans.”
“We performed an 8‐week clinical, histological and biochemical study to test the ability of tretinoin to enhance efficacy and inhibit atrophogenicity of topical corticosteroids , when used in the treatment of psoriasis.”