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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Tretinoin and Tiazofurin

supplement:

Tretinoin

Research Papers that Mention the Interaction

Tiazofurin was synergistic in cytotoxicity and in causing differentiation with ribavirin, retinoic acid , and difluorodeoxycytidine.
Pharmacy World and Science  •  2005  |  View Paper
Tiazofurin and retinoic acid together in HL-60 cells provided synergistic impact on differentiation and cytotoxicity.
Advances in enzyme regulation  •  1990  |  View Paper
Tiazofurin showed additivity or synergism with ribavirin, retinoic acid , taxol, quercetin, gemcitabin, dipyridamole and brefeldin.
Anticancer research  •  1996  |  View Paper
Since it has been shown that tiazofurin down-regulated the expression of c-Ki-ras oncogene, and retinoic acid that of the myc oncogene, the joint impact of these drugs is of clinical interest particularly in end-stage leukemia where the therapeutic usefulness of tiazofurin has recently been demonstrated.
Tiazofurin and retinoic acid synergistically induced differentiation and inhibited colony formation in HL-60 human promyelocytic leukemia cells in cell culture.
Life sciences  •  1990  |  View Paper