Possible Interaction: Tretinoin and Rabbit Allergenic Extract

“ Rabbit cell growth was inhibited by 30% when treated with concentrations of retinoic acid between 5 × 10−8M and 5 × 10−9M.”

“Polyclonal rabbit anti-IL-6 antibodies were used to block the augmenting effects of RA on Ig synthesis of adenoidal B cells.”

“ Retinoids have been reported to inhibit the production of metalloproteinases by human and rabbit synovial fibroblasts and by human skin fibroblasts.”

“ All-trans retinoic acid increased the expression of myocardin, caldesmon, 22-kDa smooth muscle cellspecific protein (SM22α), and SM-myosin heavy chains in rabbit bone marrow-derived mesenchymal stem cells, as detected by reverse transcription polymerase chain reaction (PCR).”

“Conclusion: Intraoperative single-dose administration of RA and MMC significantly prevented the development of PCO in rabbit eyes.”

“Moreover, RA caused a stimulation of osteopontin mRNA expression in isolated rabbit osteoclasts.”

“In both rat and rabbit , the AUC of all-trans-retinoic acid in maternal plasma was much reduced (factor of 9 in the rat, factor of 2 in the rabbit) after multiple application as compared to the single administration, presumably due to enzyme induction.”

“We have demonstrated that high concentrations of retinoic acid (RA) inhibit expression of the differentiated phenotypes of rabbit costal chondrocytes in culture [M. Takigawa et al. (1980) Proc.”

“Abstract An aromatic analog of retinoic acid (Ro 10-9359), a synthetic compound known to arrest development and growth of chemically-induced skin papillomas and carcinomas of mice, exerts a marked inhibitory effect on induction and development of virus-induced papilloma (Shope) of rabbit skin.”