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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Tretinoin and Polypeptides

supplement:

Tretinoin

supplement:

Polypeptides

Research Papers that Mention the Interaction

RA stimulates an increase in polypeptides of 58, 60, 65, and 70 kDa with the 58- and 65-kDa species being dephosphorylated forms of the 60- and 70-kDa species.
The Journal of Biological Chemistry  •  1997  |  View Paper
The polypeptide binds with negative cooperativity, or without cooperativity to retinoic acid and thyroid response elements respectively, but with high cooperativity to the ERE.
The Biochemical journal  •  1995  |  View Paper
Analysis of biosynthesized ALP monomers revealed that RA increased glycosylation of the polypeptides.
Journal of cellular physiology  •  2000  |  View Paper
However, treatment with retinoic acid causes a decrease in IGF I and an increase in IGF II polypeptide levels.
In contrast, 48 h exposure to retinoic acid increased IGF II polypeptide levels, possibly due to increased levels of IGF binding protein‐6.
Retinoic acid treatment for 48 h decreased IGF I polypeptide levels in the culture medium.
Journal of cellular physiology  •  1997  |  View Paper
Nevertheless, retinoic acid effectively antagonized the stimulation of protein synthesis by TGF-beta and restored control levels of synthesis at 1 x 10(-7) …-acid-treated cultures, but treatment with the TGF-beta s restored these components in coincubation cultures, again supporting the antagonistic role of the polypeptide … retinoid ….
Archives of biochemistry and biophysics  •  1992  |  View Paper
The treatment of nullipotent F9 cells with retinoic acid , which induces entodermal differentiation, activates the synthesis of these polypeptides.
Developmental biology  •  1980  |  View Paper
Abstract Retinoids at low concentrations strikingly enhance the growth-promoting activity of polypeptides like epidermal growth factor, insulin, vasopressin and fibroblast-derived growth factor and of 12-0-tetradecanoyl-phorbol-13-acetate, a potent tumour-promoting agent.
Biochemical and biophysical research communications  •  1979  |  View Paper
Retinoids also show mitogenic synergism with TPA or polypeptide growth factors.
Journal of supramolecular structure  •  1979  |  View Paper
Seventeen polypeptides were upregulated during induction; several of these were significantly regulated 48 h after the addition of retinoic acid.
Journal of cellular physiology  •  1996  |  View Paper