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Discover Supplement-Drug Interactions

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Last Updated: 5 years ago

Possible Interaction: Tretinoin and Osi 461

supplement:

Tretinoin

drug:

Osi 461

Research Papers that Mention the Interaction

Moreover, OSI-461 enhanced the ability of acyclic retinoid to induce increased cellular levels of retinoic acid receptor β and to stimulate retinoic acid response element-chloramphenicol acetyltransferase activity.
We found that the combination of as little as 1.0 μmol/L acyclic retinoid and 0.01 μmol/L OSI-461 exerted synergistic inhibition of the growth of HepG2 cells.
Clinical Cancer Research  •  2004  |  View Paper