Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Tretinoin and Eb 1089

supplement:

Tretinoin

supplement:

Eb 1089

Research Papers that Mention the Interaction

EB1089 was the most potent vitamin D3 analog; and EB1089 plus ATRA was the most potent combination decreasing the tumor mass nearly 3-fold compared to tumors of diluent control mice.
Anticancer research  •  1999  |  View Paper
Results: We confirm that EB1089 diminishes apoptosis induced by 9-cis RA in T3M4 cells.
Pancreas  •  2006  |  View Paper
However, the combination of 1 nM EB1089 with 10 nM all-trans-retinoic acid exerted a growth-inhibitory effect of 90% in Capan 1 cells and of 70% in Capan 2 cells.
British Journal of Cancer  •  1996  |  View Paper
Combination of RA and EB1089 exert synergistic growth inhibition and apoptosis induction on hepatocellular cancers cells.
Cytotechnology  •  2012  |  View Paper