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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Tretinoin
drug:
Dopachrome Isomerase
Research Papers that Mention the Interaction
“Only retinoic acid , however, was effective at inhibiting the activation of dopachrome isomerase , another regulatory enzyme in melanogenesis.”
Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers.“ Trans retinoic acid (RA), at concentrations as low as 0.1 nM, inhibited the induction of tyrosinase, dopachrome conversion factor , and melanogenesis, but had no effect on the basal levels of either enzyme or of cellular melanin content.”
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