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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Tretinoin and Dopachrome Isomerase

Research Papers that Mention the Interaction

Only retinoic acid , however, was effective at inhibiting the activation of dopachrome isomerase , another regulatory enzyme in melanogenesis.
Experimental cell research  •  1990  |  View Paper
Trans retinoic acid (RA), at concentrations as low as 0.1 nM, inhibited the induction of tyrosinase, dopachrome conversion factor , and melanogenesis, but had no effect on the basal levels of either enzyme or of cellular melanin content.
The Journal of investigative dermatology  •  1990  |  View Paper