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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Tretinoin
drug:
Bexarotene
Research Papers that Mention the Interaction
“ Bexarotene cooperated with ATRA to enhance differentiation in some AML cell lines; however, the combination of bexarotene with the PPARγ agonist rosiglitazone did not.”
Induced differentiation of acute myeloid leukemia cells by activation of retinoid X and liver X receptors“Synergism between BEX and RA was also demonstrated in vitro by cell growth inhibition assays using lymphoma cell lines.”
Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system“ Bexarotene , a member of a subclass of retinoids that selectively activates retinoid receptors, modulates several pathways essential for cognitive performance and Aβ clearance.”
Bexarotene Impairs Cognition and Produces Hypothyroidism in a Mouse Model of Down Syndrome and Alzheimer’s Disease“Interestingly, bexarotene induces the early expression of a myogenic progenitor marker, Meox1, while the expression of many RA targets is also enhanced by bexarotene.”
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