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Last Updated: 3 years ago

Possible Interaction: Tretinoin and Azelaic Acid

supplement:

Tretinoin

Research Papers that Mention the Interaction

Furthermore, RA in combination with hydroquinone or 4‐hydroxyanisole, or azelaic acid increases the potency of depigmenting agents for the treatment of melasma, actinic lentigines, and postinflammatory hypermelanosis.
Dermatologic therapy  •  2006  |  View Paper
If use of a single agent does not lead to a good response, coupling the use of a retinoid with benzoyl peroxide or with azelaic acid can have a synergistic effect.
The Western journal of medicine  •  2000  |  View Paper
Azelaic acid with tretinoin caused more skin lightening after three months than azelaic acid alone, and a higher proportion of excellent responders at the end of treatment.
Tretinoin appears to enhance this effect of azelaic acid.
Cutis  •  1996  |  View Paper