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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Tretinoin
supplement:
Alpha-Aminobutyric Acid
Research Papers that Mention the Interaction
“In a combination model, RA applied at early growth phase of CHO-K1 cells followed by addition of NaBu with lowering culture temperature at the end of stationary phase resulted in two- and threefold increase in Qp and final antibody concentration, respectively.”
“In conclusion, our results … the addition of RA … NaBu along with lowering the culture temperature can increase cell culture period as well as Qp and the final concentration of … monoclonal antibody in both CHO-K1 and CHO-S cells without any significant change in binding affinity of the mAb.”
All-trans retinoic acid in combination with sodium butyrate enhances specific monoclonal antibody productivity in recombinant CHO cell line“Treatment with ATRA and NaBu synergistically attenuated the expression of α-SMA and PCNA and reduced systolic blood pressure in Npr1+/− mice.”
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