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Last Updated: 2 years ago

Possible Interaction: Trehalose and Temozolomide

supplement:

Trehalose

Research Papers that Mention the Interaction

Along with a direct … mechanisms may explain how trehalose … TMZ‐ and IR‐induced effects: the remarkable trehalose‐stimulated autophagy in A375 cells, which were sensitive to TMZ‐ and IR‐induced … trehalose‐stimulated premature senescence in SK‐Mel‐28 cells, which were resistant to apoptosis and less prone to autophagy.
In long‐term experiments, colony‐forming capacity was dramatically reduced by trehalose , and even more by combined trehalose + TMZ or trehalose + IR.
We tested whether trehalose , a natural glucose disaccharide proved to induce autophagy, could enhance the effect of TMZ and ionizing radiation (IR).
Journal of cellular physiology  •  2019  |  View Paper