“Here, we provide evidence that supplementation with a non-reducing disaccharide, namely trehalose , enhanced the viability of S. boulardii exposed to an oxidative environment by preventing metacaspase YCA1-mediated programmed cell death through inhibition of intracellular ROS production.”
“Our results suggest that supplementation with S. boulardii together with trehalose could increase the viability of the organism, and thus should improve its effectiveness as a probiotic and as a treatment for acute diarrhea and other gastrointestinal disorders.”